Hertfordshire & West Essex Area Prescribing Committee (HWE APC) – summary of recommendations

The HWE APC newsletter with outputs from the October 2025 meeting are available here. HWE APC is the local decision-making group for medicines.

The top line recommendations/outputs likely to have most impact on primary care are listed below. Refer to the newsletter for further details/links.

• Dapagliflozin (generic) preferred SGLT2 inhibitor choice
• Tirzepatide (Mounjaro®) for obesity update
• Hypertension guidelines in adults update
• Acetylcysteine and carbocisteine for reduction of sputum viscosity
• Blood glucose and ketone meters, test strips and lancet guidance update
• Mirabegron for treating neurogenic detrusor overactivity in people 3 to 17 years DOUBLE RED
• Prescribing guidelines for people over 50 years with or at risk of osteoporosis – update
• Homemade supplements – update
• Thickeners & Thickened Oral Nutritional Supplements (ONS) – update
• Reusable insulin pen guidance – update
• Cenobamate for treating focal onset seizures in epilepsy – AMBER INITIATION
• Calcium acetate for hyperphosphatemia – update